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What isMetformin? Metformin is an oral drug prescribed for people diagnosed with type 2 Diabetes. It is sometimes used in fertility health to treat polycystic ovary syndrome (PCOS). The drug is available in both tablet and solution form. Metformin is often prescribed to obese patients and is used together with other drugs and proper dietary and exercise program to help control glucose levels in adults.

Metformin Dosage Guide

Type 2 Diabetes is an illness whereby the body produces insufficient insulin or otherwise the insulin produced is defective. This results in elevated levels of blood sugar in the body, a condition known as hyperglycemia.

Is Metformin available in generic form?

Metformin is the generic version manufactured under different brand names. The most common are Fortamet, Glumetza, Riomet, and metformin hydrochloride which is marketed as Glucophage which is also the most common generic medication. Generic metformin is available on accredited online drug selling or rx delivery sites such as The drug is costly but so are most diabetic medications.

How does it work?

Metformin belongs to a class of drugs called Biguanides. This class of drugs generally has a similar mode of action which is to control the levels of bold sugar in the body. Metformin works by restoring the normal response of your body towards insulin. Insulin is a hormone naturally produced by your body to help flush out extra sugar from the blood. It also plays a major role in regulating the amount of sugar produced in the liver and the amounts absorbed by the intestines.


The dosage will differ with each patient, but often, your healthcare provider will prescribe starting with a low dosage either once or twice daily and subsequently increases the dosage if necessary. In case you miss a dose, and it’s time to take the next, take only one dose to avoid an overdose. The adult dosage includes a 500 mg tablet of hydrochloric metformin taken twice daily, in the morning and in the evening. The dosage is taken with meals to lower blood glucose levels in the patient.

The drug is not approved to be prescribed to children below the age of 10. As for children above 10, the initial dosage is 500mg twice daily with a maximum of 2000 mg daily.

Janumet vs. metformin

Janumet is a combination of two drugs, metformin and sitagliptin. The drug is used by people with type 2 diabetes to lower blood sugar levels in the body. Janumet is the generic form of Metformin hydrochloride.

Side effects

The most common side effects associated with metformin include:

  • Belching
  • Bloating
  • Indigestion
  • Cramping
  • Diarrhea
  • Stomach upset
  • Vomiting
  • Passing gas
  • Acidic stomach
  • Reduced appetite
  • Weight loss
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Interactions with other drugs

Metformin oral medication might interact with other medications to produce different effects.

Taking metformin while on other diabetes medication might cause low blood sugar levels. Ensure to tell your doctor of any other diabetes medication that you might be taking such as insulin or other medications such as glyburide that release insulin. The doctor may reduce your metformin dosage in such a scenario.

Metformin and blood pressure

Diuretics such as furosemide and hydrochlorothiazide which used in treating blood pressure might increase your sugar levels. They might interfere with the effectiveness of metformin.

Calcium blockers such as nifedipine used to lower blood pressure increase metformin levels in the body. This may, in turn, increase the risk of side effects associated with metformin

Hormonal drugs, thyroid agents and nicotinic acids might reduce the effectiveness of metformin causing hyperglycemia.


Ensure to take the dosage as prescribed once or twice daily as instructed. To reduce the intensity of side effects, your doctor will often direct you to start at a low dosage and increase it with time if necessary. Ensure to inform your doctor of any other medication you might be taking before starting metformin dosage.

Patients with severe kidney problems should not take this medication. Reduced dosage will be prescribed if the condition is mild.

Metformin should is not used to treat type 1 diabetes

Pregnant or lactating women should notify their doctors if they are under Metformin medication. However, the drug does not have any serious effect on the baby.

Olha Yasna